Example media interest

February 2024: Elife and University of Cambridge Press Release on Knights et al. paper on functional compensation in older brains.
Januray 2024: Webinar by Rik Henson for British Society for Research on Ageing on effects of lifestyle and cardiovascular health on brain and cognition.
July 2023: BBC “Stay Young” series with Michael Mosley, featuring interview with CamCAN participant and report of some CamCAN findings.
Dec 2020: BBC Radio 4 interview for All in the Mind about importance of mid-life activities for old-age cognition.
Jan 2020: Article in Mathworks newsletter about advantage of Matlab software for CamCAN imaging analysis.
Aug 2018: Article in Daily Mail about mid-life activities relating to late-life cognitive health.
May 2015: Articles in Science Daily and Health Imaging about individual differences in brain activity.
Dec 2014: Articles in Daily Mail and The Times about effect of age on executive functions.
Jun 2014: BBC interview on Radio 4 about CamCAN.
Sep 2012: Podcast by Naked Scientists about CamCAN.

BBSRC Cam-CAN Promotional Films

In July 2013 the BBSRC released 5 short promotional videos about Cam-CAN:

Recent, example Cam-CAN Recorded Talks

Scientific Publications from the CamCAN Team

Below are just those publications from the CamCAN team; for the full list of >200 publications using CamCAN data (e.g, by other research groups), please see PubMed Citations.

Preprints

King, D.L.O., Henson, R.N., Correia, C., Rowe, J.B., Tsvetanov, K.A. Pulse Pressure impairs cognition via white matter disruption. MedRXiv Open Access Preprint.
Kearney, J.F., Qualter, P., Cam-CAN, Taylor, J. Cognitive Mediation of Social Engagement and Socioeconomic Background: SEM Exploration in Cam-CAN, a Large Adult Lifespan Database. PsyRXiv Open Access Preprint.
Bingjiang, L., Tsvetanov, K.A., Tyler, L.K., Clarke, A., Cam-CAN, Amos, W. Genetic signatures of human brain structure: A comparison between GWAS and relatedness-based regression. BioRxiv. [Cam-CAN Author list 13] Open Access Preprint
Demetriou, I., Bridge, L., Emery, T., Attaheri, A., Henson, R. Comparison of online versus paper versions of cognitive tests in the CamCAN study of adult ageing. PsyRXiv Open Access Preprint.

2025

Nagrodzki, J., Passamonti, L., Schweizer, S., Stretton, J., Knights, E., Henson, R., Wolpe, N. (2025). Behavioural and brain differences in the processing of negative emotion in previously depressed individuals: an exploratory analysis of population-based data. Emotion. [Cam-CAN Author list 15] DOI

2024

Henson, R.N., Olszowy, W., Tsvetanov, K.A., Cam-CAN, Zeidman, P. (2024). Evaluating models of the ageing BOLD response. Human Brain Mapping. [Cam-CAN Author list 15] DOI
Knights, E., Henson, R.N., Morcom, A.M, Mitchell, D.J. & Tsvetanov, K.A. (2024). Neural Evidence of Functional Compensation for Fluid Intelligence in Healthy Ageing. Elife [Cam-CAN Author list 15] DOI
Raykov, P., Knights, E., Cam-CAN, Henson, R.N. (2024). Does functional system segregation mediate the effects of lifestyle on cognition in older adults? Neurobiology of Aging, 134, 126-134. [Cam-CAN Author list 15] DOI

2023

Henriques, R.N., Henson, R.N., Cam-CAN, Correia, M.M. (2023). Unique information from common diffusion MRI models about white-matter differences across the human adult lifespan. Imaging Neuroscience, 1. [Cam-CAN Author list 15] DOI
McCormick, E.M., Cam-CAN, Kievit, R.A. (2023). Poorer White Matter Microstructure Predicts Slower and More Variable Reaction Time Performance: Evidence for a Neural Noise Hypothesis in a Large Lifespan Cohort. Journal of Neuroscience, 43. [Cam-CAN Author list 15] DOI
Lugtmeijer, S., Geerligs, L., Tsvetanov, K.A., Mitchell, D.J., Cam-CAN & Campbell, K.L. (2023). Lifespan differences in visual short-term memory load-modulated functional connectivity. Neuroimage, 270, 119982. [Cam-CAN Author list 14] DOI
King, D.L.O., Henson, R.N., Kievit, R., Wolpe, N., Brayne, C., Tyler, L.K., Rowe, J.B., Cam-CAN & Tsvetanov, K.A. (2023). Distinct components of cardiovascular health are linked with age-related differences in cognitive abilities. Scientific Reports, 13:978. [Cam-CAN Author list 14] DOI
Mitchell, D., Mousley, A., Shafto, M., Cam-CAN, Duncan, J. (2023). Neural contributions to reduced fluid intelligence across the adult lifespan. Journal of Neuroscience [Cam-CAN Author list 14] DOI
Guardia, T., R.N., Mazloum-Farzaghi, N., Olsen, R.K., Tsvetanova, K., Campbell, K.L. (2023). Associative memory is more strongly predicted by age-related differences in the prefrontal cortex than medial temporal lobes. [Cam-CAN Author list 15] DOI
Liu, X., Tyler, L.K., Cam-CAN, Davis, S.W., Rowe, J.B., Tsvetanov, K.A. (2023). Cognition’s dependence on functional network integrity with age is conditional on structural network integrity. Neurobiology of Aging, 129, 195-208 [Cam-CAN Author list 14] DOI

2022

Wu, S., Tyler, L.K., Henson, R.N., Rowe, J.B., Cam-CAN, Tsvetanov, K.A. (2022). Cerebral blood flow predicts multiple demand network activity and fluid intelligence across the adult lifespan. Neurobiology of Aging, 121, 1-14 [Cam-CAN Author list 14] DOI
Liu, X., Tyler, L.K., Cam-CAN, Rowe, J.B., Tsvetanov, K.A. (2022). Multimodal fusion analysis of functional, cerebrovascular and structural neuroimaging in healthy aging subjects. Human Brain Mapping, 43, 5490-5508 [Cam-CAN Author list 14] DOI
Bethlehem et al. (2022). Brain charts for the human lifespan. Nature, 604, 7904. [Cam-CAN Author list 14] DOI
Tomassini, A., Hezemans, F.H., Ye, R., Tsvetanov, K.A., Wolpe, N. & Rowe, J.B. (2022). Prefrontal Cortical Connectivity Mediates Locus Coeruleus Noradrenergic Regulation of Inhibitory Control in Older Adults. Journal of Neuroscience, 42, 3484-3493. [Cam-CAN Author list 13] DOI
Stretton, J., Schweizer, S., Dalgleish, T. & Cam-CAN (2022). Age-related enhancements in positive emotionality across the lifespan: structural equation modelling of brain and behaviour. Journal of Neuroscience. [Cam-CAN Author list 13] DOI
Kocagoncu, E., Nesbitt, D., Emery, T., Hughers, L., Henson, R. & Rowe, J. (2022). Neurophysiological and brain structural markers of cognitive frailty differ from Alzheimer’s disease. Journal of Neuroscience, 42, 1362-1373. [Cam-CAN Author list 13] PubMed
Tibon, R. & Tsvetanov, K.A. (2022). The Neural Shift of Sleep Quality and Cognitive Aging: A Resting-State MEG study of Transient Neural Dynamics. Frontiers in Aging Neuroscience. [Cam-CAN Author list 13] PubMed DOI

2021

Knights, E., Morcom, A., Cam-CAN & Henson, R. (2021) Does Hemispheric Asymmetry Reduction in Older Adults (HAROLD) in motor cortex reflect compensation? Journal of Neuroscience, 41, 9361-9373. [Cam-C Author list 13] PubMed
Tibon, R., Tsevtanov, K.A., Price, D., Nesbitt, D., Cam-CAN & Henson, R.N. (2021). Transient neural network dynamics in cognitive ageing. Neurobiology of Aging, 105, 217-228. [Cam-CAN Author list 13] PubMed

2020

Tsvetanov, K.A., Henson, R.N.A., Jones, S., Mutsaerts, H-J., Fuhrmann, D., Tyler, L.K., Cam-CAN, & Rowe, J.B. (2020). The effects of age on resting-state BOLD signal variability is explained by cardiovascular and neurovascular factors. Psychophysiology, 13714. [Cam-CAN Author list 13] Open Access
Liu, K.Y, Kievit, R.A., Tsvetanov, K.A., Betts, M.J., Duzel, E., Rowe, J.B. Cam-CAN, Howard, R. & Hammerer, D. (2020). Noradrenergic-dependent functions are associated with age-related locus coeruleus signal intensity differences. Nature Communications, 1712. [Cam-CAN Author list 13] Open Access
Bethlehem, R., Paquola, C., Seidlitz, J., Ronan, L., Bernhard, B., Cam-CAN & Tsvetanov, K.A. (2020). Dispersion of functional gradients across the adult lifespan. Neuroimage, 117299. [Cam-CAN Author list 13] Open Access
Lehmann, B.C.L., Henson, R.N., Geerligs, L., Cam-CAN & White, S.R. (2020). Characterising group-level brain connectivity: A framework using Bayesian exponential random graph models. Neuroimage, 117480. [Cam-CAN Author list 13] Open Access
Henson, R.N., Suri, S., Knights, E., Rowe, J.B., Kievit, R.A., Lyall, D.M., Chan, D., Eising, E. & Fisher, S.E. (2020). Effect of APOE polymorphism on cognition and brain in the CamCAN cohort. Brain and Neuroscience Advances, 4, 1-12. [Cam-CAN Author list 13]. Stage 2 Registered Report.
Borgeest, G., Henson, R., Shafto, M., Samu, D., Cam-CAN, Kievit, R. (2020). Greater lifestyle engagement is associated with healthy cognitive ageing. PLOS ONE, 15, e0230077. [Cam-CAN Author list 12]
Strommer, J.M., Davis, S.W., Henson, R.N., Tyler, L.K., Cam-CAN & Campbell K.L. Physical activity predicts population-level age-related differences in frontal white matter (2020). The Journals of Gerontology: Biological Sciences, 2, 236-243. [Cam-CAN Author list 12] Open Access.
Wolpe, N., Ingram, J.N., Tsvetanov, K.A, Henson, R.N, Wolpert, D.M., Cam-CAN, Rowe, J. (2020). Age-related reduction in motor adaptation: brain structural correlates and the role of explicit memory. Neurobiology of Aging, 90, 13-23 [Cam-CAN Author list 13]

2019

Shafto MA, Henson RN, Matthews FE, Taylor JR, Emery T, Erzinclioglu S, Hanley C, Rowe JB, Cusack R, Calder AJ, Marslen-Wilson WD, Duncan J, Dalgleish T, Brayne C, Cam-CAN, Tyler LK. (2019). Cognitive Diversity in a Healthy Aging Cohort: Cross-Domain Cognition in the Cam-CAN Project. J Aging Health. [Cam-CAN Author list 12] Open Access.
Schweizer, S., Stretton, J., Van Belle, J., Price, D., Calder, A.J., Cam-CAN and Dalgleish, T. (2019). Age-related decline in emotional positivity and emotion regulation in a population-derived cohort. Social Cognitive and Affective Neuroscience, 623-631 [Cam-CAN Author list 12] Open Access.
Bruffaerts, R., Tyler, L.K., Shafto, M., Tsvetanov, K.A., Cam-CAN and Clarke, A. (2019). Perceptual and conceptual processing of visual objects across the adult lifespan. Scientific Reports, 9:13771. [Cam-CAN Author list 12] Open Access.
Fuhrmann, D., Nesbitt, D., Shafto, M., Rowe, J.B., Price, D., Gadie, A., Cam-CAN, Kievit, R.A. (2019). Cardiovascular risk factors for micro- and macro-structural brain changes in healthy ageing. Neurobiology of Aging, 74, 46-55. [Cam-CAN Author list 12] Open Access.
Liu, K.Y., Acosta-Cabronero, J., Cardenas-Blanco, A., Loane, C., Berry, A.J., Betts, M.J., Kievit, R.A., Henson, R.N., Duzel, E., Cam-CAN, Howard, R., Hammerer, D. (2019). In vivo visualization of age-related differences in the locus coeruleus. Neurobiology of Aging, 74, 101-111. [Cam-CAN Author list 12] Open Access.
Bardouille, T., Bailey, L. Cam-CAN. Evidence for age-related changes in sensorimotor neuromagnetic responses during cued button pressing in a large open-access dataset (2019). Neuroimage, 193, 25-34. [Cam-CAN Author list 12] Open Access

2018

Chan, D., Shafto, M., Kievit, R., Matthews, F., Spink, M., Valenzuela, M., Cam-CAN and Henson, R.N. (2018). Lifestyle activities in mid-life contribute to cognitive reserve in late-life, independent of education, occupation and late-life activities. Neurobiology of Aging, 70, 180-183. [Cam-CAN Author list 12] Open Access.
de Mooij, S. M. M., Henson, R. N., Waldorp, L. J., Kievit, R. A.. (2018). Age differentiation within grey matter, white matter and between memory and white matter in an adult lifespan cohort. Journal of Neuroscience, 38, 5826-5836. [Cam-CAN Author list 12] Open Access.
Morcom, A. CamCAN, Henson, R. N. (2018). Increased prefrontal activity with aging reflects nonspecific neural responses rather than compensation. Journal of Neuroscience, 1701-1717. [Cam-CAN Author list 12] Open Access
Tsvetanov, K., Ye, Z., Samu, D., Treder, M.S., Wolpe, N., Tyler, L.K., Rowe, J.R., CamCAN (2018). Activity and connectivity differences underlying inhibitory control across the adult lifespan. Journal of Neuroscience, 38, 7887-7900. [Cam-CAN Author list 12] Open Access
Green, E., Bennett, H., Brayne, C., Cam-CAN, Matthews, F.E. (2018). Exploring patterns of response across the lifespan: the Cambridge Centre for Ageing and Neuroscience (Cam-CAN) study. BMC Public Health, 18:760. [Cam-CAN Author list 12] Open Access.
Wolpe N, Zhang J, Nombela C, Ingram JN, Wolpert DM, Cam-CAN, Rowe JB (2018). Sensory attenuation in Parkinson’s disease is related to disease severity and dopamine dose. Scientific Reports, 8, 15643 [Cam-CAN Author list 12] Open Access.
Geerligs, L, Cam-CAM, Campbell, K. L. (2018). Age-related differences in information processing during movie watching. Neurobiology of Aging, 72, 106-120. [Cam-CAN Author list 12] Open Access.
Liu, K.Y., Acosta-Cabronero, J., Cardenas-Blanco, A., Loane, C Berry, A.J., Betts, M.J., Kievit, R.A., Henson, R.N., Duzel, E., Cam-CAN, Howard, R.,Hammerer, D. (2018). In vivo visualization of age-related change in the locus coeruleus. Neurobiology of Aging, 17, 101-111. [Cam-CAN Author list 12] Open Access.
Mitchell, D. J., Cam-CAN, and Cusack, R. (2018). Visual short-term memory through the lifespan: Preserved benefits of context and metacognition. Psychology and Aging, 33(5), 841-854. [Cam-CAN Author list 12] Open Access.

2017

Lehmann, B., White, S., Henson, R., Cam-CAN, Geerligs, L. (2017). Assessing dynamic functional connectivity in heterogeneous samples. NeuroImage. 157, 635-647. [Cam-CAN Author list 12] Open Access
Schweizer, S., Kievit, R. A., Emery, T., Cam-CAN, and Henson, R. N. (2017). Symptoms of Depression in a Large Healthy Population Cohort are related to Subjective Memory Complaints and Memory Performance in Negative Contexts. Psychological Medicine. 1-11. doi:10.1101/101642 [Cam-CAN Author list 12] Open Access
Geerligs, L., Tsvetanov, K., Cam-CAN and Henson, R.N. (2017). Challenges in measuring individual differences in functional connectivity using fMRI: the case of healthy aging. Human Brain Mapping. 38, 4125-4165. [Cam-CAN Author list 12] Open Access
Price, D., Tyler, L. K., Neto Henriques, R., Campbell, K. R., Williams, N., Treder, M., Taylor, J., Cam-CAN, Henson, R. (2017). Age-Related Delay in Visual and Auditory Evoked Responses is Mediated by White- and Gray-matter Differences. Nature Communications 8, 15671. [Cam-CAN Author list 12] PDF.
Samu, D., Campbell, K., Tsvetanov, K., Shafto, M., Cam-CAN, and Tyler, L. K. (2017). Preserved cognitive functions with age are determined by domain-dependent shifts in network responsivity. Nature Communications. 8, 14743. [Cam-CAN Author list 12] Open Access
Gadie, A., Shafto, M., Leng, Y., Cam-CAN, Kievit, R. A. (2017). Age-related differences in self-reported sleep quality predict healthy ageing across multiple domains: a multi-modal cohort of 2406 adults. BMJ Open. 7(7). Open Access [Cam-CAN Author list 12].
Taylor, J.R., Williams, N., Cusack, R., Auer, T., Shafto, M.A., Dixon, M., Tyler, L.K., Cam-CAN, Henson, R.N. (2017). The Cambridge Centre for Ageing and Neuroscience (Cam-CAN) data repository: Structural and functional MRI, MEG, and cognitive data from a cross-sectional adult lifespan sample. NeuroImage. 144, 262-269. doi: 10.1016/j.neuroimage.2015.09.018. [Cam-CAN Author list 12]. PDF

2016

Wolpe, N., Ingram, J., Tsvetanov, K., Geerligs, L., Kievit, R., Henson, R., Wolpert, D., Cam-CAN & Rowe, J. (2016). Ageing increases reliance on sensorimotor prediction through structural and functional differences in frontostriatal circuits. Nature Communications, 7. [Cam-CAN Author list 12] Open Access
Kievit, R. A., Davis, S. W., Griffiths, J., Correia, M., Cam-CAN, Henson, R. N. A. (2016). A watershed model of individual differences in fluid intelligence. Neurophychologia. [Cam-CAN Author list 12] PDF
Henson, R.N., Campbell, K.L., Davis, S.W., Taylor, J.R., Emery, T., Erzinclioglu, S., Cam-CAN & Kievit, R.A. (2016). Multiple determinants of lifespan memory differences. Scientific Reports, 6(32527) [Cam-CAN Author list 12] PDF
Phillips, H., Blenkmann, A., Hughes, L. E., Kochen, S., Bekinschtein, T. A., Cam-CAN, Rowe, J. B. (2016). Convergent evidence for hierarchical prediction networks from human electrocorticography and magnetoencephalography. Cortex. 82, pp. 192-205. [Cam-CAN Author list 12] PDF
Ronan, L., Alexander-Bloch, A. F., Wagstyl, K., Farooqi, S., Brayne, C., Tyler, L. K., Cam-CAN, Fletcher, P. C. (2016). Obesity associated with increased brain-age from mid-life. Neurobiology of Ageing. [Cam-CAN Author list 12] PDF
Geerligs, L., Cam-CAN & Henson, R.N. (2016). Functional connectivity and structural covariance between regions of interest can be measured more accurately using multivariate distance correlation. Neuroimage, 135, 16-31. [Cam-CAN Author list 12] PDF
Shafto, M. A., James, L. E., Abrams, L., Cam-CAN. Tyler, L. K. (2017). Age-Related Increases in Verbal Knowledge Are Not Associated With Word Finding Problems in the Cam-CAN Cohort: What You Know Won’t Hurt You. Journals of Gerontology B: Psychological Sciences. 72(1), 100-106. DOI: 10.1093/geronb/gbw074. [Cam-CAN Author list 12]. PDF
Campbell, K. L., Samu, S., Davis, S. W., Geerligs, L., Mustafa, A., Cam-CAN, Tyler, L. K. (2016). Robust Resilience of the Frontotemporal Syntax System to Aging. Journal of Neuroscience. 36(19): 5214-5227; doi: 10.1523/JNEUROSCI.4561-15.2016. [Cam-CAN Author list 12]. PDF
Tsvetanov, K. A., Henson, R. N. A., Tyler, L. K., Razi, A., Geerligs, L., Ham, T., CamCAN, Rowe, J. (2016). Extrinsic and intrinsic brain network connectivity maintains cognition across the lifespan despite accelerated decay of regional brain activation. The Journal of Neuroscience. 36(11), 3115-3126. [Cam-CAN Author list 12]. PDF

2015

Green, E., Shafto, M. A., Matthews, F. E., Cam-CAN., White, S. R. (2015). Adult Lifespan Cognitive Variability in the Cross-Sectional Cam-CAN Cohort. International Journal of Environmental Research and Public Health. 2015, 12(12), 15516-15530. DOI: 10.3390/ijerph121215003. [Cam-CAN Author list 12]. PDF
Campbell, K. L., Shafto, M.A., Wright, P., Tsvetanov, K.A., Geerligs, L., Cusack, R., Cam-CAN, & Tyler, L.K. (2015). Idiosyncratic responding during movie-watching predicted by age differences in attentional control. Neurobiology of Aging. DOI: 10.1016/j.neurobiolaging.2015.07.028 [Cam-CAN Author list 11]. PDF
Geerligs, L., Rubinov, M., Cam-CAN, & Henson, R.N. (2015). State and trait components of functional connectivity: individual differences vary with mental state. Journal of Neuroscience, 35(41), 13949-13961. DOI:10.1523/jneurosci.1324-15.2015 [Cam-CAN Author list 11]. PDF
Tsvetanov, K.A., Henson, R.N.A., Tyler, L.K., Davis, S.W., Shafto, M., Taylor, J.R., Williams, N., Cam-CAN, & Rowe, J.B. (2015). The effect of ageing on fMRI: correction for the confounding effects of vascular reactivity evaluated by joint fMRI and MEG in 335 adults. Human Brain Mapping, 36(6), 2248-2269. DOI: 10.1002/hbm.22768 [Cam-CAN Author list 11]. PDF

2014

Shafto, M.A., Tyler, L.K. (2014). Language in the aging brain: The network dynamics of cognitive decline and preservation. Science, 346(6209), pp. 583-587. DOI: 10.1126/science.1254404. PDF
Kievit, R.A., Davis, S.W., Mitchell, D.J., Taylor, J.R., Duncan, J., Cam-CAN, & Henson, R.N.A. (2014). Distinct aspects of frontal lobe structure mediate age-related differences in fluid intelligence and multitasking. Nature Communications, 5, 5658. DOI: 10.1038/ncomms6658.[Cam-CAN Author list 7]. PDF
Shafto, M.A., Tyler, L.K., Dixon, M., Taylor, J.R., Rowe, J.B., Cusack, R., Calder, A.J., Marslen-Wilson, W.D., Duncan, J., Dalgleish, T., Henson, R.N., Brayne, C., Cam-CAN, & Matthews, F.E. (2014). The Cambridge Centre for Ageing and Neuroscience (Cam-CAN) study protocol: a cross-sectional, lifespan, multidisciplinary examination of healthy cognitive ageing. BMC Neurology, 14(204).doi:10.1186/s12883-014-0204-1.[Cam-CAN Author list 10].PDF

Cam-CAN Corporate Author membership

The Cam-CAN project involves many different researcher and support staff whose efforts are acknowledged in publications and presentations under the Cam-CAN corporate authorship.

A record of the Cam-CAN corporate author members appropriate for each output can be accessed by clicking on the ‘Cam-CAN Author list x’ links above.